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Peer-Reviewed Literature • Discovery Timelines • Scientist Directory • Experiment Studio
Dr. Jennifer Doudna • 2024
CRISPR-Cas9 has revolutionized genomic editing. This paper investigates target cleavage efficiencies in mammalian cells, detailing biochemical techniques to optimize Cas9 binding and mitigate off-target cleavage by over 90%.
Research Team • 2023
Hydrothermal vents support complex biological communities in the complete absence of sunlight. We trace primary productivity pathways driven by sulfur-oxidizing bacterial endosymbiosis.
Research Team • 2023
This paper reviews how short-chain fatty acids (SCFAs) produced by intestinal bacterial fermentation regulate host insulin sensitivity, GLP-1 hormone secretion, and metabolic balance.
Dr. Jennifer Doudna • 2024
CRISPR-Cas9 has revolutionized genomic editing. This paper investigates target cleavage efficiencies in mammalian cells, detailing biochemical techniques to optimize Cas9 binding and mitigate off-target cleavage by over 90%.
Research Team • 2023
This paper reviews how short-chain fatty acids (SCFAs) produced by intestinal bacterial fermentation regulate host insulin sensitivity, GLP-1 hormone secretion, and metabolic balance.
James Watson & Francis Crick • 1953
We wish to suggest a structure for the salt of deoxyribose nucleic acid (D.N.A.). This structure has two helical chains each coiled round the same axis.
Dr. Kary Mullis • 1986
Description of an automated thermostable DNA amplification procedure utilizing repeated cycles of denaturation, primer annealing, and extension by Thermus aquaticus polymerase.
Rosalind Franklin • 1953
X-ray diffraction photograph of sodium thymonucleate structure B showing definitive coaxial double helical parameters with outer phosphate positioning.
Research Team • 2024
The accumulation of amyloid-beta plaques between cerebral neurons is a major hallmark of Alzheimer's disease. We review secretase processing pathways and hyperphosphorylated Tau neurofibrillary tangles.
Research Team • 2023
Hydrothermal vents support complex biological communities in the complete absence of sunlight. We trace primary productivity pathways driven by sulfur-oxidizing bacterial endosymbiosis.